AstraZeneca
Engineer Any Professional Degree Drug Development: Discovery Chemistry &
Screening
Job
Description
We
have exciting opportunities for pipeline pilot based technical team member to
impact Drug Discovery projects, working as part of global Discovery Chemistry
and Screening within the Science & Enabling unit’s IT department.
The
purpose of the service is to provide a set of well-maintained applications
supporting R&D processes at all R&D sites. The applications are
anything from local to global and non-regulated, non-critical to critical and
regulated.
The
effect of the service is to ensure stability and reliability of applications.
It delivers ongoing maintenance and changes if required covering both
commercial (COTS) and in-house developed (Bespoke) applications.
The
purpose of the service team is to provide an agile, responsive and
knowledgeable Application Service to AZ Research & Development community
globally across all R&D sites.
Each
member of the team should be focusing on positive business outcomes and
customer satisfaction in each interaction with the user community.
The
service is coordinated globally and provides support, maintenance and
availability of in scope applications through local support teams at major
R&D sites to allow direct interaction with customers. AZ Chennai supports
applications used from early Discovery phases to late stage Clinical, safety
and regulatory and safety. The applications are running on either cloud or AZ
supported platforms and clients e.g. Windows 7, Vista, Lab PC and Linux
workstations.
The
service manages enhancements, changes and releases into the R&D application
estate in a controlled and coordinated
way.
These
set of applications provide novel approaches for scientists to generate models
of data and to archive such models to communicate these to drug projects.
Accountabilities/Responsibilities:
The
scope of the service covers a large set of scientific solutions. It is essential to have a good understanding
of the business context and the R&D Processes where the solutions are being
used. Working with a specific application often requires in-depth understanding
of the business process and scientific awareness in all R&D Domains.
Analyzing
and further developing Algorithms as well as business workflows are a common
activity in the team.
The
pipeline pilot based technical team member will work closely with the technical
team lead, operational service manager and the E2E capability service manager
to ensure sophisticated and on-time delivery and service of the different
applications. He/she will also collaborate closely with different application
support teams, vendors, scientists driving the delivery of world class IT
services. He/she will be responsible for ensuring Application Support teams
deliver services according to the defined business requirements, adhere to
AstraZeneca global standards, agreed Service Level Agreements and are managed
in accordance to the IT Service Delivery Framework (ITIL).
To
be successful in delivery, he/she must work very closely with the Application
specialists and the Middleware specialist in the infrastructure teams, when
resolving incidents and problems as well as when testing and deploying new
version of application code or Middleware components.
Another
important part of a successful delivery of the service is the close and direct
relation with our customers. Each team member will have regular contact with
our customers via phone, IM’s or email.
We
expect all members of the team to work in an Agile and Lean way, using fit for
purpose, low overhead processes to underpin the work.
Main
responsibilities
· Should take ownership of application
management for the clinical or regulatory domain
· Operational delivery of Application
Management services to the agreed service levels (SLA), including the planning
of daily and long-term team capacity management activities.
· Ensuring that the IT Service Delivery
Framework is adhered to by your team members under their jurisdiction
(Incident, problem, change, and release management)
· Application availability Management. Understand
the Customers' requirements for IT service availability, mapping this to the
capabilities of all the elements of the technology stack to ensure that
availability targets in all areas are measured and achieved, and that they
match or exceed the current and projected needs of the business.
· Ensuring that the applications and their
underlying platforms are monitored in accordance with application needs and
best practice.
· Ensuring bugs/ defects are identified and
remediated. Ensuring that the operational impact of any proposed solution is
understood and agreed where appropriate.
· Operational execution of the recovery
actions detailed in the application recovery plan.
· Implementation of patches which have been
identified by appropriate third parties and for the successful application of
the patch in adherence to the IT Support Framework. Operational impacts need to
be understood and agreed where appropriate.
This includes ensuring that a full
technical assessment for the underlying platforms is completed.
· Implementation of application upgrades
· Operationally managing all middleware and
application components, increasing capacity as required and needed, in a
proactive approach.
· Completing the Application Life Cycle
plans for individual applications, which incorporate all attributes of the
technology stack, to the required level of detail and any investment plans
required.
· Recommending continuous improvement
solutions to the technical team lead, Operational Service Manager and E2E Capability Service Manager. These
recommendations are based on analysis of trends identified through service
operation, monitoring and outputs from service health checks.
· Maintaining and updating all documentation
associated to the service throughout its lifecycle, including but not limited
to AZBORG and CMDB
· A key stakeholder in accepting the service
into live operation through the Service Introduction Process.
· Reviewing the performance of the
applications within the capability and agreeing mitigation actions and where
appropriate with the Service Line Lead.
· Undertaking the application risk
management activity and communicating and agreeing the aggregated risk
position.
· Producing an aggregated performance report
that is linked to the business performance reporting such that IT performance
can be clearly aligned to business outcome.
· Any audit, providing information, data
etc.
· Application rationalization. Recommending
rationalization opportunities when application functionality or technology is
the same. Executing the activities to rationalize.
· Decommissioning and Service Retirement,
executing the Process and completing the decommissioning activities for middleware
and application components.
Essential
Skills:
The
candidate should essentially demonstrate:
Knowledge
on maintaining the Pipeline Pilot Platform which includes installation (around
2-6 years of pipeline pilot platform and protocol development)
Licensing
and its renewal, administration of the platform and the web ports.
Adequate
knowledge on Oracle PL SQL.
Experience
in developing / maintaining Biovia Pipeline pilot protocols is mandatory
Experience
with and knowledge of Chemo Informatics/ Bioinformatics.
Preferable
to have candidates with education in Bio/ Chemo Informatics. Excellent written
and verbal communication skills.
Perform
work without significant direction.
MANDATORY
SKILLS : Oracle Database Programming, Biovia Pipeline Pilot
DESIRED
SKILLS : Bio Informatics, Chemo Informatics, Knowledge of Open Eye Toolkit, Schrodinger,
Gaussian, Biovia Draw
EDUCATIONAL
BACKGROUND: Any Professional Degree
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